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What side effects appeared in recent US clinical trials for olaparib? Recent US clinical trials for olaparib reported anemia, fatigue, nausea, vomiting, and diarrhea as the most common side effects. Anemia occurred in 41% of patients overall and in 21% grade 3 or higher cases. Fatigue appeared in 30% of patients. Nausea reached 58%, vomiting 30%, and diarrhea 34%. Grade 3 or higher versions of these gastrointestinal issues remained low at roughly 2–3%.
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