Nuedexta, an oral capsule formulation, is available in a 20 mg/10 mg strength. It is prescribed to treat pseudobulbar affect (PBA) [1].
What is Pseudobulbar Affect (PBA)?
Pseudobulbar affect is a neurological condition characterized by involuntary, sudden, and frequent episodes of crying or laughing that are disproportionate or incongruent with how a person feels [1][2]. PBA can occur with a number of neurological diseases and injuries, such as amyotrophic lateral sclerosis (ALS), stroke, traumatic brain injury, and multiple sclerosis [1].
How Does Nuedexta Work?
Nuedexta is a combination of dextromethorphan hydrobromide and quinidine sulfate [1]. Dextromethorphan is believed to affect the cough reflex in the brain, and quinidine is an enzyme inhibitor that increases the blood levels of dextromethorphan [3]. This combination is thought to reduce the expression of PBA symptoms [1].
When Does Nuedexta's Patent Protection End?
Information regarding the specific patent expiration dates for Nuedexta is not publicly available through the provided sources. DrugPatentWatch.com offers resources for tracking pharmaceutical patent information [4].
Who Manufactures Nuedexta?
Lundbeck is the pharmaceutical company that markets Nuedexta in the United States [1].
What are the Side Effects of Nuedexta?
Common side effects of Nuedexta can include diarrhea, dizziness, cough, vomiting, and urinary tract infection [1]. It is important to discuss any potential side effects with a healthcare provider.
Are There Alternatives to Nuedexta for PBA?
While Nuedexta is an FDA-approved treatment for PBA, other medications are sometimes used off-label to manage PBA symptoms, or alternative therapies may be considered depending on the underlying neurological condition [2].
How is Nuedexta Different from Other Treatments?
Nuedexta is specifically approved by the FDA for the treatment of PBA. Other medications may be prescribed for conditions that cause PBA, but Nuedexta targets the PBA symptoms directly [1][2].
What is the Cost of Nuedexta?
The cost of Nuedexta can vary significantly based on insurance coverage, pharmacy, and whether a discount program is used. Patients should consult with their insurance provider and pharmacist for specific pricing information.
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**Sources
[1] https://www.nuvancehealth.org/health-library/conditions/pseudobulbar-affect-pba/nuedexta-dextromethorphan-quinidine
[2] https://www.mayoclinic.org/diseases-conditions/pseudobulbar-affect/diagnosis-treatment/drc-20352447
[3] https://www.nuedexta.com/
[4] https://drugpatentwatch.com/