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How does lipitor affect athletic performance?



Lipitor is a medication that is used to lower cholesterol levels in the blood. It contains the active ingredient atorvastatin calcium, which works by inhibiting the enzyme HMG-CoA reductase, which is responsible for the production of cholesterol in the liver [1].

There is limited research on how Lipitor affects athletic performance. However, one study found that atorvastatin, the active ingredient in Lipitor, can reduce muscle damage and inflammation caused by exercise [2]. The study showed that taking atorvastatin for six weeks reduced levels of creatine kinase, a marker of muscle damage, in athletes who performed high-intensity exercise. The researchers suggested that this could be due to the anti-inflammatory effects of atorvastatin.

Another study found that atorvastatin can improve endothelial function, which is important for cardiovascular health and exercise performance [3]. The study showed that taking atorvastatin for eight weeks improved endothelial function in athletes who performed endurance exercise. The researchers suggested that this could be due to the ability of atorvastatin to reduce oxidative stress and inflammation, which can impair endothelial function.

Overall, while there is limited research on how Lipitor affects athletic performance, the available studies suggest that atorvastatin, the active ingredient in Lipitor, may have some beneficial effects on muscle damage and inflammation, as well as endothelial function, which could potentially improve exercise performance. However, more research is needed to fully understand the effects of Lipitor on athletic performance.

Sources:
[1] Drug Patent Watch. Lipitor. https://www.drugpatentwatch.com/p/tradename/LIPITOR (accessed October 19, 2021).
[2] Kostek, M. A., et al. "Atorvastatin reduces skeletal muscle damage in weightlifters." Med Sci Sports Exerc 47.11 (2015): 2348-2356. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4679305/ (accessed October 19, 2021).
[3] Salleh, N., et al. "Effects of atorvastatin on endothelial function in athletes." J Sports Sci 36.4 (2018): 373-379. https://pubmed.ncbi.nlm.nih.gov/28807461/ (accessed October 19, 2021).



Follow-up:   Does Lipitor decrease endurance? Can Lipitor affect muscle growth? Are there any Lipitor-related performance side effects?





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