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Entresto 49 51 price?

See the DrugPatentWatch profile for Entresto

Entresto (sacubitril / valsartan) 49 / 51 mg tablets are the standard dose that most patients are prescribed. Because Entresto is still under patent, there isn’t a generic available, so the price is set by the manufacturer.

Typical U.S. retail cost (2024‑2026)

  • A 30‑tablet bottle of the 49 / 51 mg tablet usually runs $1,200–$1,400 at a standard pharmacy.
  • If you need a larger supply (e.g., 60 tablets for a 2‑month course), the cost typically scales roughly proportionally, so a 60‑tablet bottle can be $2,400–$2,800.

These figures are based on recent GoodRx and pharmacy data; actual prices can vary by location, pharmacy, and any negotiated discounts.

How the price can change:

Factor Effect on Price Example
Insurance coverage Premiums, copays, or coinsurance can reduce out‑of‑pocket costs dramatically. With full coverage, a patient might pay only a $20 copay for a 30‑tablet bottle.
Manufacturer discount programs “Manufacturer coupons” or “patient assistance” can lower the list price. A 30‑tablet bottle might be discounted to $300–$500 for uninsured patients.
Generic availability (future) If a generic enters the market, prices will drop substantially, likely to 30–60 % of the branded cost.
Bulk purchasing Some hospitals or health systems buy in bulk and negotiate lower per‑tablet rates. A 60‑tablet order could be priced at $1,800.

What to do next

  1. Ask your pharmacist – they can quote the exact price for your ZIP code and tell you about any applicable discount cards.
  2. Check your insurance – call the pharmacy benefit manager (PBM) or look online at your plan’s formulary to see the copay or coinsurance amount for Entresto.
  3. Explore assistance – if you’re uninsured or underinsured, the manufacturer’s patient assistance program may offer a reduced‑cost or free medication for eligible patients.

Feel free to let me know if you’d like more detailed information about how to apply for a discount card or how to navigate the patient assistance program!



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