Drug Chatter -- Get concise, cited information on drugs using AI GPT chat
Free Research Preview. DrugChatter may produce inaccurate information.

Ka for acetic acid?

See the DrugPatentWatch profile for acetic

What is the Ka (acid dissociation constant) for acetic acid?

For acetic acid (CH3COOH), the acid dissociation constant (Ka) is commonly given as about 1.8 × 10⁻⁵ at 25 °C. [1]

Why does Ka for acetic acid depend on conditions?

Ka is temperature-dependent because it’s derived from the equilibrium:
CH3COOH ⇌ H⁺ + CH3COO⁻.
Different references (and different temperatures like 0 °C vs 25 °C) report slightly different Ka values, even though they describe the same acid dissociation process. [1]

How does Ka relate to pKa for acetic acid?

Because pKa = -log10(Ka), the Ka value above corresponds to a pKa of about 4.74 at 25 °C. [1]

What’s the corresponding Kb for acetate (the conjugate base)?

If you need the base dissociation constant (Kb) for acetate (CH3COO⁻), it can be found using:
Ka × Kb = Kw (where Kw ≈ 1.0 × 10⁻¹⁴ at 25 °C).
Using Ka ≈ 1.8 × 10⁻⁵ gives Kb ≈ 5.6 × 10⁻¹⁰ at 25 °C. [1]

Sources

  1. https://en.wikipedia.org/wiki/Aceticacid#Equilibriumand_thermodynamics


Other Questions About Acetic :

aminoacetic acid 1.5% in plastic container discount aminoacetic acid 1.5% in plastic container Acetic acid price trends? Price of acetic acid per ton? Acetic acid price trends? Acetic anhydride production cost? United states acetic acid market?