Is weight a factor in nivolumab's fixed dosing?

No – the current standard dosing for nivolumab is a fixed dose, not weight‑based. In practice it’s given as 240 mg IV every 2 weeks or 480 mg IV every 4 weeks, regardless of the patient’s weight. The older weight‑based regimens (e.g., 3 mg/kg) were used in earlier clinical trials, but most guidelines now recommend the fixed schedule because it’s simpler, has comparable efficacy and safety, and is supported by phase 3 data.