Does cosentyx dosage change for obese patients?

Does the dosage of Cosentyx change for obese patients?

Cosentyx is given as 300 mg once a month after the first five weekly doses. This schedule applies to adults with plaque psoriasis, psoriatic arthritis, ankylosing spondylitis, and non-radiographic axial spondyloarthritis. The official prescribing information does not include any weight-based adjustments or higher doses for obese patients.

How does weight affect Cosentyx dosing?

No clinical studies submitted to the FDA have shown that body weight influences the exposure or efficacy of Cosentyx. The manufacturer states that population pharmacokinetic analyses found no clinically significant effect of body weight on secukinumab exposure.