What are the risks of sleepwalking with Ambien?
Sleepwalking, also known as somnambulism, has been associated with the use of certain sedatives, including benzodiazepines and non-benzodiazepines like Ambien (zolpidem). According to the Ambien label [1], "complex behaviors" (including sleepwalking) are a potential risk associated with the medication.
How common is sleepwalking with Ambien?
Studies suggest that sleepwalking can occur with any sedative, including Ambien. However, the exact incidence rate is not well-established. One postmarketing surveillance study published in the New England Journal of Medicine reported that 1.4% of patients taking Ambien experienced "complex sleep-related behaviors" [2], but the study did not specifically define sleepwalking.
Why is Ambien more likely to cause sleepwalking?
The exact mechanism is unclear, but Ambien's unique pharmacological properties may contribute to increased sleepwalking risk. Unlike some other sedatives, Ambien has a shorter half-life, which can lead to a steeper decline in effects during the night, potentially increasing the likelihood of complex behaviors.
Who is at risk of sleepwalking with Ambien?
While anyone taking Ambien may be at risk, some individuals appear to be more susceptible. These include:
* Older adults
* People with a history of sleepwalking (known as somnambulistic tendency)
* Patients who consume excessive amounts of alcohol while taking Ambien
Can stopping Ambien prevent sleepwalking?
Yes. Stopping or reducing Ambien use may alleviate sleepwalking episodes in many cases. Patients should report any occurrences of sleepwalking to their healthcare provider, who can adjust their treatment plan as necessary.
Are there alternatives to Ambien that reduce sleepwalking risk?
Yes. Other non-benzodiazepine sedatives, such as Lunesta (eszopiclone) and Sonata (zaleplon), may carry a lower risk of sleepwalking. Patients should consult their healthcare provider to determine the most suitable alternative.
Important note
Always consult a healthcare provider before altering your medication regimen or using alternative treatments.
Sources:
[1] https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/020634Orig1s045bl.pdf
[2] Schenck, C. H., & Montplaisir, J. (2012). Sleep and sleep disorders in neurology. New England Journal of Medicine, 366(22), 2106-2116.