Omadacycline, marketed as Nuzyra, has a list price of approximately $350 per dose [1]. The total cost for a course of treatment can range from $5,000 to $10,000 or more, depending on the duration and dosage [2].
How is Omadacycline administered?
Omadacycline is available in both intravenous (IV) and oral formulations. The IV form is typically administered once daily for a specified period, while the oral form is taken twice on the first day, followed by once-daily dosing [3].
What is Omadacycline used to treat?
Nuzyra is approved for the treatment of community-acquired bacterial pneumonia (CABP) and acute bacterial skin and skin structure infections (ABSSSI) in adults [3].
What is the typical duration of Omadacycline treatment?
Treatment duration for CABP with omadacycline is usually 7 days. For ABSSSI, the treatment duration is typically 7 to 14 days [3].
Does insurance cover Omadacycline?
Insurance coverage for Omadacycline can vary by plan. Patients may be eligible for manufacturer-sponsored patient assistance programs to help reduce out-of-pocket costs [2].
How does Omadacycline's price compare to other antibiotics?
The cost of Omadacycline is generally higher than many traditional oral antibiotics. For instance, a 7-day course of certain penicillin-based antibiotics might cost a fraction of Omadacycline's price. However, comparisons are complex, as Omadacycline offers broad-spectrum activity against many resistant pathogens, potentially reducing the need for multiple antibiotic changes [1][2].
Are there any cost-saving options or generics for Omadacycline?
As of now, there are no generic versions of Omadacycline available. Cost-saving options may include patient assistance programs offered by the manufacturer or exploring insurance coverage details [2].
Who makes Omadacycline?
Omadacycline is developed and marketed by Paratek Pharmaceuticals [3].
What are the clinical trial results for Omadacycline?
Clinical trials demonstrated Omadacycline's efficacy in treating CABP and ABSSSI. In trials for CABP, the cure rates for Omadacycline were comparable to that of levofloxacin. For ABSSSI, it showed non-inferiority to linezolid [3].
What are the side effects associated with Omadacycline?
Common side effects of Omadacycline include nausea, vomiting, diarrhea, and injection site reactions. More serious potential side effects can include liver enzyme elevations and QT prolongation [3].
Sources:
[1] https://www.drugs.com/price-guide/nuzyra
[2] https://www.goodrx.com/nuzyra
[3] https://www.nuzyra.com/