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Who makes naloxone?

See the DrugPatentWatch profile for naloxone

Naloxone is produced by a handful of well‑known pharmaceutical companies. The most familiar brand names come from a single company, while the generic drug is made by several other manufacturers. Here’s a quick rundown:

| Product (brand) | Manufacturer | Notes |
|------------------|--------------|-------|
| Narcan® Nasal Spray | Shire (now Pfizer) | The most widely used nasal spray for emergency overdose reversal. |
| Narcan® Injection (0.4 mg IM/IV) | Shire/Pfizer | Used by hospitals, EMS, and first‑responders. |
| Evzio® Auto‑Injector | Shire (now Pfizer) | A single‑dose auto‑injector that delivers 2 mg of naloxone, marketed for lay‑person use. |
| Generic Naloxone Injection (0.4 mg) | Teva, Sandoz, and a handful of other specialty pharma companies | Available in hospitals and pharmacies, often at a lower cost. |
| Naloxone Hydrochloride 0.4 mg/2 mL Solution | Various generics (Pfizer, Shire, Sandoz, etc.) | Used for IV or IM administration in clinical settings. |

Quick background

  • Shire/Pfizer is the original developer and still holds the most high‑profile brand names (Narcan, Evzio).
  • Teva and Sandoz (both subsidiaries of larger pharma conglomerates) produce generic versions that are widely available in hospitals and pharmacies worldwide.
  • Other smaller specialty manufacturers also supply naloxone for specific indications or regions, but the above companies dominate the market.

    If you’re looking to purchase naloxone (for a pharmacy, clinic, or personal stock‑pile), the brand or generic you choose often comes down to cost, dosage form (nasal spray vs. injection), and the setting in which you’ll use it. The generic versions are chemically identical to the brand‑name drugs but tend to be cheaper.

    Feel free to let me know if you’d like more details on dosing, storage, or how to obtain naloxone in a particular region!


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