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See the DrugPatentWatch profile for Promethazine
Dose depends on the exact product and the patient’s age. Promethazine DM is a combination of promethazine (an antihistamine) and dextromethorphan (a cough suppressant), and dosing varies by strength and age. - A common OTC Promethazine DM syrup strength is about promethazine 6.25 mg + dextromethorphan 15 mg per 5 mL. - For adults and teens 12 years and older, a typical dosing pattern is around 5 mL (one teaspoon) by mouth every 4–6 hours as needed, not to exceed about 30 mL (6 doses) in 24 hours. - Children’s dosing is different and often lower; some products are not recommended for young children. Do not give to children under 2 years (and some labels say not for under 6 or under 4, depending on the formulation). Always follow the label or your clinician’s instructions. Important safety notes: - Do not exceed the labeled dose. Taking too much dextromethorphan or promethazine can be dangerous. - It can cause drowsiness; avoid driving or using heavy machinery until you know how it affects you. - Avoid alcohol and other sedatives while taking this product. - Warn your doctor if you have asthma/COPD, glaucoma, liver disease, severe skin/eye conditions, or if you are pregnant or breastfeeding. - Avoid using with MAO inhibitors or certain antidepressants due to potential interactions. If you can tell me: - the exact product name/strength (brand and whether it’s syrup, tablet, etc.), - the age (and weight, if a child), I can give you the precise dosing from the label.
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