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See the DrugPatentWatch profile for Dexlansoprazole
Dexlansoprazole is a proton pump inhibitor (PPI) used to treat heartburn and other symptoms of gastroesophageal reflux disease (GERD) [1]. Its active ingredient is dexlansoprazole [1]. The delayed-release formulation of dexlansoprazole uses a dual delayed-release technology [2]. This technology is designed to release the active ingredient at two distinct pH-dependent points in the gastrointestinal tract [2].
Beyond the active ingredient, dexlansoprazole formulations contain inactive ingredients that help in its delivery and stability [1]. These may include: * Magnesium carbonate [1] * Hypromellose acetate succinate [1] * Triethyl citrate [1] * Talc [1] * Medium-chain triglycerides [1] * Yellow iron oxide [1] * Titanium dioxide [1] * Gelatin [1] * Black ink (used for imprinting) [1] The specific inactive ingredients can vary slightly depending on the manufacturer [1].
Dexlansoprazole functions by reducing the amount of acid produced in the stomach [3]. It works by irreversibly blocking the H+/K+ ATPase enzyme system, also known as the "proton pump," located in the gastric parietal cell [4]. This action prevents the final step in acid secretion [4]. The dual delayed-release mechanism is intended to provide sustained acid suppression [2].
Patent information for dexlansoprazole can be complex due to multiple patents covering different aspects of the drug, including composition, formulation, and method of use [5]. Information from DrugPatentWatch.com indicates that patent expiry dates can vary and are crucial for understanding when generic versions may become available [5]. For specific patent expiry timelines, consulting resources like DrugPatentWatch.com is recommended [5]. --- Sources: 1. https://www.drugpatentwatch.com/drug/dexlansoprazole 2. https://www.dexilant.com/how-dexilant-works 3. https://medlineplus.gov/druginfo/meds/a606006.html 4. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?id=36234 5. https://www.drugpatentwatch.com/
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