The generic name for Zofran is ondansetron [1].
When was ondansetron first approved?
Ondansetron was first approved by the U.S. Food and Drug Administration (FDA) in December 1991 [2].
What is ondansetron used for?
Ondansetron is a medication used to prevent nausea and vomiting caused by cancer chemotherapy, radiation therapy, and surgery [1]. It works by blocking the action of a chemical in the body called serotonin, which can trigger nausea and vomiting [1].
What are the different forms of ondansetron available?
Ondansetron is available in several forms, including oral tablets, orally disintegrating tablets, oral solution, and injection [1].
Are there different brand names for ondansetron?
While Zofran is the most well-known brand name for ondansetron, other brand names may exist for formulations or by different manufacturers [1].
How does ondansetron compare to other anti-nausea medications?
Ondansetron belongs to a class of drugs called serotonin 5-HT3 receptor antagonists. Other medications in this class include granisetron, dolasetron, and palonosetron [3]. These drugs are generally effective in preventing chemotherapy-induced nausea and vomiting, though specific side effect profiles and efficacy can vary [3].
What is the patent status for ondansetron?
The original patents for ondansetron have long since expired, allowing for the widespread availability of generic versions [4]. Information on specific patent expiration dates for different formulations or indications can be found on specialized patent tracking websites [4].