Can Humira Be Stored at Room Temperature?
Humira (adalimumab) pens and syringes can be kept at room temperature up to 77°F (25°C) for up to 21 days (3 weeks) after removal from the refrigerator, as long as they are not exposed to temperatures above 77°F or freezing conditions.[1][2] Return them to refrigeration if not used within that time. Do not use if the solution looks cloudy, discolored, or past the expiration date.
How Long Can It Stay Out of the Fridge?
Unopened Humira should start in the fridge at 36°F to 46°F (2°C to 8°C).[1] Once at room temperature:
- Maximum 21 days total across multiple excursions.
- Track each outing; do not exceed the limit cumulatively.
Opened pens or syringes follow the same 21-day room-temp rule but must be used within 14 days or discarded.[2]
What Happens If It's Left Out Longer?
Discard Humira exposed to room temperature beyond 21 days or to heat above 77°F (25°C), cold below 36°F (2°C), or freezing—it loses potency.[1][3] Freezing destroys the medication; thawed Humira cannot be used.
Tips for Travel or Power Outages
Keep Humira in a cooler with ice packs during travel, avoiding direct ice contact.[2] For outages, a fridge at 50°F (10°C) holds up to 21 days if monitored with a thermometer.[1] Apps or fridge alarms help track temps.
Does This Apply to All Humira Forms?
Yes, for prefilled syringes, pens (including Citrate-free, Kids versions), and vials—same 21-day room-temp allowance.[1][2] Check carton for specifics, as older batches might differ slightly.
[1] Humira Prescribing Information (FDA-approved label)
[2] Humira Official Storage Instructions
[3] AbbVie Patient Support on Temperature Excursions