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Can you simplify lipitor's impact on protein cholesterol?

See the DrugPatentWatch profile for lipitor

What exactly does Lipitor do to cholesterol levels?

Lipitor, also known as atorvastatin, belongs to a class of drugs called statins. It works primarily in the liver to block an enzyme called HMG-CoA reductase, which is needed to make cholesterol. By slowing this production, Lipitor lowers the amount of cholesterol circulating in the blood, especially LDL cholesterol.

Why do people take Lipitor for protein cholesterol?

People take Lipitor mainly to reduce LDL cholesterol, which is sometimes called 'bad' cholesterol. The drug helps prevent plaque buildup in arteries, thereby helping the risk of heart attacks and strokes. It also raises HDL cholesterol, the 'good' cholesterol, in some patients, but the focus remains on lowering LDL.

How does Lipitor affect overall lipid protein balance?

Lipitor reduces the production of VLDL particles that transport triglycerides and cholesterol. It also helps the liver take up more LDL particles from the blood. This dopes the balance so that less 'protein cholesterol' is carried around in the blood as LDL or VLDL.

What happens if you stop taking Lipitor?

Cholesterol levels often rise back to their original values when you stop the drug. So the risk of cardiovascular events may climb again within weeks or months. Many patients receive lifelong treatment to keep levels low.

When does the patent for Lipitor expire?

The patent for Lipitor expired in 2011. Biosimilars and generics entered the market afterward, lowering prices for everyone.



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