Lacosamide is a medication used to treat epilepsy, neuropathic pain, and other conditions. According to Drug Patent Watch [1], the drug has been approved by the US FDA since 2008. Lacosamide has been shown to be effective in reducing seizure frequency in patients with partial-onset seizures [3]. However, the safety of long-term use of lacosamide is still a matter of debate.

A study published in the journal Epilepsia [3] examined the safety and efficacy of lacosamide over a period of 5 years. The study found that lacosamide was generally well-tolerated, with no significant safety concerns observed over the long term. The most common side effects were dizziness, headache, and nausea. The study concluded that lacosamide is a safe and effective treatment option for patients with epilepsy.

Another study published in the journal Clinical Drug Investigation [2] also examined the long-term safety of lacosamide. The study found that lacosamide was generally well-tolerated, with no significant safety concerns observed over a period of up to 8 years. The study also found that lacosamide was effective in reducing seizure frequency in patients with epilepsy.

In conclusion, based on the available evidence, lacosamide appears to be a safe and effective treatment option for patients with epilepsy and other conditions. While some studies have shown that lacosamide is generally well-tolerated over a period of up to 8 years, further research is needed to fully understand the long-term safety of the drug. Patients should always consult with their healthcare provider before starting or stopping any medication.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LACOSAMIDE
[2] https://link.springer.com/article/10.1007/s40261-019-00845-7
[3] https://onlinelibrary.wiley.com/doi/full/10.1111/epi.13502