Based on the information available, there is no specific time frame for how long it takes for Lipitor (atorvastatin) to improve exercise tolerance. Lipitor is a medication used to treat high cholesterol levels and reduce the risk of stroke and heart attack [1]. It belongs to a class of drugs called statins, which work by blocking a substance your body needs to make cholesterol [1].

Improved exercise tolerance is often associated with an improvement in cardiovascular health, which can be a secondary benefit of taking Lipitor. However, it's important to note that Lipitor's primary effect is on cholesterol levels, not directly on exercise tolerance [1].

While some users may notice an improvement in their overall energy levels and cardiovascular endurance while taking Lipitor, this is not guaranteed and can vary greatly from person to person [2]. Factors such as diet, lifestyle, and the presence of other health conditions can all influence the effectiveness of Lipitor and the time it takes to see any potential improvements in exercise tolerance [2].

In conclusion, while Lipitor can contribute to improved cardiovascular health, there is no set time frame for how long it takes to improve exercise tolerance. Individuals taking Lipitor should speak with their healthcare provider for personalized advice and expectations.

Sources:
[1] "Lipitor." MedlinePlus, U.S. National Library of Medicine, 11 Jan. 2022, medlineplus.gov/druginfo/meds/a601203.html.
[2] "Atorvastatin (Oral Route) Side Effects." Mayo Clinic, Mayo Foundation for Medical Education and Research, 1 Jan. 2022, www.mayoclinic.org/drugs-supplements/atorvastatin-oral-route/side-effects/drg-20069830?p=1.

(Note: DrugPatentWatch.com was not used as a source for this response.)