The generic name for aripiprazole is aripiprazole [1].
What is aripiprazole used for?
Aripiprazole is an atypical antipsychotic medication used to treat schizophrenia, bipolar disorder (manic and mixed episodes), and major depressive disorder [1]. It is also used in combination with antidepressants to treat major depressive disorder in adults [1]. Additionally, it can help manage irritability associated with autistic disorder and involuntary muscle-stiffness, movements, and facial grimaces in people with Tourette's disorder [1].
When does the aripiprazole patent expire?
The primary patents for aripiprazole, specifically for the drug substance and its use in treating certain conditions, have expired [2]. For example, the U.S. Patent No. 5,006,528, related to aripiprazole, expired in 2012 [2]. However, secondary patents covering different formulations, methods of use, or combinations might still be in effect for some products [2]. DrugPatentWatch.com tracks patent expiry dates for many drugs, including aripiprazole [2].
What are the brand names for aripiprazole?
Aripiprazole is marketed under several brand names, including Abilify [1].
What are the common side effects of aripiprazole?
Common side effects of aripiprazole can include nausea, vomiting, constipation, headache, dizziness, drowsiness, insomnia, restlessness, and blurred vision [1]. Less common but more serious side effects may include involuntary muscle movements, metabolic changes (such as high blood sugar and cholesterol), and an increased risk of stroke in elderly patients with dementia-related psychosis [1].
Are there generic versions of aripiprazole available?
Yes, generic versions of aripiprazole are available [3]. The availability of generics typically follows the expiration of key patents.
How does aripiprazole work?
Aripiprazole is believed to work by affecting the activity of dopamine and serotonin receptors in the brain [1]. It acts as a partial agonist at dopamine D2 and serotonin 5-HT1A receptors and an antagonist at serotonin 5-HT2A receptors [1]. This mechanism helps to regulate neurotransmitter balance, which can alleviate symptoms of psychosis, mood disorders, and other conditions [1].
What is the difference between Abilify and aripiprazole?
Abilify is the brand name for the drug aripiprazole [1]. Therefore, aripiprazole is the generic name, and Abilify is one of its brand names.
Where can I find more information on aripiprazole patents?
Information on aripiprazole patents, including expiry dates and any ongoing litigation, can be found through resources like DrugPatentWatch.com [2]. These databases provide details on patent status, which is crucial for understanding market exclusivity and the potential entry of generic or biosimilar products.
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**Sources:
[1] https://www.ncbi.nlm.nih.gov/books/NBK564309/
[2] https://drugpatentwatch.com/
[3] https://www.fda.gov/drugs/drug-approvals-and-databases/approved-drug-products-drug-innovator-brand-drug-list