See the DrugPatentWatch profile for Olodaterol
Olodaterol is marketed under the brand name Striverdi Respimat [1]. It is a long-acting beta-agonist (LABA) used in the management of chronic obstructive pulmonary disease (COPD) [2].
What is Striverdi Respimat used for?
Striverdi Respimat is prescribed as a long-term maintenance bronchodilator treatment to relieve symptoms in patients with COPD [2]. It helps to relax the muscles in the airways, making breathing easier for individuals experiencing shortness of breath due to COPD [2].
How does olodaterol work?
Olodaterol is a selective agonist of beta-2 adrenergic receptors. When inhaled, it stimulates these receptors in the smooth muscle of the airways. This stimulation leads to relaxation of the bronchial muscles, causing bronchodilation and improving airflow [2].
When did Striverdi Respimat become available?
Striverdi Respimat received U.S. Food and Drug Administration (FDA) approval in July 2015 [3].
What is the patent status of olodaterol?
Information regarding specific patent expiry dates for olodaterol can be found on patent tracking websites such as DrugPatentWatch.com [4]. These resources track patent filings, grants, and expirations, which are critical for understanding market exclusivity.
What other medications are similar to Striverdi Respimat?
Other LABAs used for COPD management include indacaterol (Arnuity Ellipta), salmeterol (Serevent Diskus), and formoterol (Perforomist, Symbicort) [2]. Striverdi Respimat is often used in combination with tiotropium, another long-acting bronchodilator from the anticholinergic class, under the brand name Stiolto Respimat [5].
What are the potential side effects of Striverdi Respimat?
Common side effects associated with Striverdi Respimat include nasopharyngitis, cough, and pain in the mouth and throat [2]. As with all LABAs, there is a potential risk of paradoxical bronchospasm [2].
Can Striverdi Respimat be used for asthma?
Striverdi Respimat is specifically indicated for the maintenance treatment of COPD and is not approved for the treatment of asthma [2].
How is Striverdi Respimat administered?
Striverdi Respimat is delivered using the Respimat inhaler device, which provides a slow-moving mist [1]. Patients are instructed to inhale the medication once daily [2].
What is the mechanism of action of Striverdi Respimat compared to other COPD medications?
Striverdi Respimat works by relaxing airway smooth muscles, similar to other LABAs. This mechanism differs from anticholinergics, which also help to open airways by blocking acetylcholine. Combination therapies, like Stiolto Respimat, use both mechanisms to provide more comprehensive bronchodilation [5].
What is the difference between Striverdi Respimat and Stiolto Respimat?
Striverdi Respimat contains only olodaterol, a LABA. Stiolto Respimat is a combination product containing both olodaterol (a LABA) and tiotropium (a long-acting muscarinic antagonist), offering a dual mechanism of bronchodilation [5].
Where can I find more information on olodaterol drug patents and market exclusivity?
DrugPatentWatch.com provides detailed information on drug patents, including those related to olodaterol, which can help in understanding potential generic entry timelines and market exclusivity [4].
Sources
- Striverdi Respimat [Internet]. Boehringer Ingelheim. [cited 2024 May 14]. Available from: https://www.boehringer-ingelheim.us/patient-care/our-products/respiratory/striverdi-respimat
- Olodaterol [Internet]. National Library of Medicine. [cited 2024 May 14]. Available from: https://medlineplus.gov/druginfo/meds/a614036.html
- FDA approves Striverdi Respimat for COPD [Internet]. U.S. Food and Drug Administration. 2015 Jul 27. [cited 2024 May 14]. Available from: https://www.fda.gov/drugs/drug-approvals/fda-approves-striverdi-respimat-copd
- DrugPatentWatch.com [Internet]. [cited 2024 May 14]. Available from: https://www.drugpatentwatch.com/
- Stiolto Respimat [Internet]. Boehringer Ingelheim. [cited 2024 May 14]. Available from: https://www.boehringer-ingelheim.us/patient-care/our-products/respiratory/stiolto-respimat