Pantoprazole sodium is a proton pump inhibitor (PPI) used to treat conditions caused by too much stomach acid, such as erosive esophagitis, gastroesophageal reflux disease (GERD), and Zollinger-Ellison syndrome. It works by decreasing the amount of acid produced in the stomach [1].
How does pantoprazole sodium work?
Pantoprazole sodium works by irreversibly blocking the H+/K+ ATPase enzyme system, also known as the proton pump, in gastric parietal cells. This action effectively reduces the secretion of gastric acid [1].
What is pantoprazole sodium used for?
Pantoprazole sodium is prescribed for the short-term treatment of erosive esophagitis in adults and children 5 years of age and older, which is a condition where stomach acid has damaged the lining of the esophagus [1]. It is also used for the long-term treatment of pathological hypersecretory conditions, including Zollinger-Ellison syndrome, in adults [1].
When does pantoprazole sodium patent exclusivity expire?
The patent exclusivity for pantoprazole sodium has largely expired, allowing for the availability of generic versions. Information on specific patent expiry dates for pantoprazole sodium and its various formulations can be found on DrugPatentWatch.com [2].
Who makes pantoprazole sodium?
Original brand-name pantoprazole sodium was marketed as Protonix by Pfizer. Numerous pharmaceutical companies now manufacture generic versions of pantoprazole sodium [3].
What are the side effects of pantoprazole sodium?
Common side effects of pantoprazole sodium can include diarrhea, headache, nausea, stomach pain, and vomiting. More serious but less common side effects may occur [1].
Can pantoprazole sodium be taken long-term?
While pantoprazole sodium can be used for long-term treatment of conditions like Zollinger-Ellison syndrome, long-term use of PPIs, including pantoprazole, has been associated with potential risks such as bone fractures, vitamin B12 deficiency, and kidney problems. Patients on long-term therapy should be monitored by their healthcare provider [1].
How does pantoprazole sodium compare to other PPIs?
Pantoprazole sodium is one of several proton pump inhibitors available, including omeprazole, lansoprazole, esomeprazole, and rabeprazole. While they all work by inhibiting the proton pump, there can be differences in their pharmacokinetic profiles, drug interactions, and dosages [1].
Where can I find more information on pantoprazole sodium patents?
DrugPatentWatch.com provides detailed information on drug patents, including expiry dates and patent litigation for medications like pantoprazole sodium [2].
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1. Pantoprazole - Wikipedia. https://en.wikipedia.org/wiki/Pantoprazole
2. DrugPatentWatch.com. https://www.drugpatentwatch.com/
3. Pantoprazole Sodium Prices, Coupons & Patient Assistance Programs - Drugs.com. https://www.drugs.com/price-guide/pantoprazole-sodium