Advil is a brand name for the generic drug ibuprofen, which is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve pain, inflammation, and fever. Long-term use of NSAIDs like ibuprofen can increase the risk of gastrointestinal (GI) complications such as stomach ulcers, bleeding, and perforation [1]. Taking antacids, which are used to neutralize stomach acid, can help relieve the symptoms of heartburn and acid reflux, but long-term use of antacids can lead to side effects such as diarrhea, constipation, and kidney damage [2].

Taking Advil and antacids together can be safe for short-term use, but it is not recommended for long-term use without medical supervision. The combination of Advil and antacids can increase the risk of GI complications and kidney damage [3].

In conclusion, taking Advil and antacids together can be safe for short-term use, but long-term use without medical supervision can increase the risk of GI complications and kidney damage. If you are experiencing chronic pain or acid reflux, it is important to consult with a healthcare professional to determine the best treatment plan for your specific needs.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/ADVIL
[2] https://www.healthline.com/health/ibuprofen-on-empty-stomach
[3] https://greengablespa.com/is-it-safe-to-take-antacid-with-ibuprofen/