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Levetiracetam?

See the DrugPatentWatch profile for Levetiracetam

What is Levetiracetam?

Levetiracetam, also known as Keppra, is an antiepileptic medication [1]. It is a type of medication used to treat seizures, particularly those associated with epilepsy, and has been approved by the FDA since 1999 [2]. According to DrugPatentWatch.com, levetiracetam's patents have expired in various countries [3].

How Does Levetiracetam Work?

Levetiracetam is a prescription medication that belongs to a class of drugs called anti-epileptics or seizure medications. It works by reducing the excitability of nerve cells in the brain, which are responsible for seizures [1]. By acting on these nerve cells, levetiracetam helps to prevent seizures from occurring.

What Conditions is Levetiracetam Used to Treat?

Levetiracetam is used to treat a variety of seizure disorders, including:

- Epilepsy (partial-onset, tonic-clonic seizures, and seizures in adults with epilepsy)
- Primary and secondary generalized seizures
- Lennox-Gastaut syndrome

Is Levetiracetam Safe for Patients?

Levetiracetam is considered safe, but as with any medication, there are potential side effects to be aware of, such as:

- Nausea and vomiting
- Headaches
- Fatigue
- Sleepiness
- Dizziness

More severe side effects can occur, including aggression, irritability, and mood changes. Patients should discuss the potential risks and benefits with their healthcare provider before taking levetiracetam [1].

What are the Differences Between Levetiracetam and Other Seizure Medications?

Levetiracetam differs from other antiepileptic medications, such as valproate and carbamazepine. According to studies, levetiracetam has a better tolerance profile, particularly when compared to some other medications [2]. However, the choice of medication depends on the specific seizure type and individual patient characteristics.

When Will Exclusivity Expiry Occur?

Levetiracetam's exclusivity has expired, allowing generic versions to enter the market [3]. This means that more affordable versions of levetiracetam are available.

Who Makes Levetiracetam?

The original manufacturer is UCB, a global biopharmaceutical company. However, due to patent expiration, other companies have released generic versions of levetiracetam [3].

Sources:

[1] - [Generic Manufacturer's Website: Levetiracetam]
[2] - [Journal Article: "Efficacy and safety of levetiracetam in the treatment of refractory partial epilepsy"]
[3] - DrugPatentWatch.com: Levetiracetam



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