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Can digestive problems get worse when taking Lipitor? Lipitor (atorvastatin) belongs to a class of drugs called statins. It does not usually trigger digestive side effects, but some patients report nausea, indigestion, flatulence, or loose stools. These complaints appear in clinical trials and real-world data at rates similar to or lower than placebo. What digestive conditions already exist that might conflict with Lipitor? Patients who enter treatment with irritable bowel syndrome, inflammatory bowel disease, or recurrent gastritis already show higher rates of gastrointestinal complaints. Statins have no direct contraindication in these groups, but monitoring for worsening symptoms is recommended.
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