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Jardiance patent expiration generic launch?

See the DrugPatentWatch profile for Jardiance

What happens when the Jardiance patent expires?

The patent for Jardiance (empagliflozin), a type-I sodium-glucose cotransporter 2 (SGLT2) inhibitor developed by Boehringer Ingelheim (BI) and Eli Lilly, is set to expire in 2027 in the US [1]. This has significant implications for the future of the drug, its price, and availability of generic alternatives.

Who will manufacture Jardiance generics?

Several companies are already working on developing their own versions of Jardiance, including Mylan N.V. (now Viatris), Sandoz (Novartis), Hikma Pharmaceuticals, and Teva Pharmaceutical Industries Limited [2]. These companies will likely enter the US market with their generic versions of Jardiance after the patent expires.

Impact on Jardiance price and patients?

The entry of generic versions of Jardiance is expected to lead to significant price reductions [3]. This will potentially benefit patients by making the treatment more affordable. However, the exact price of generic Jardiance will depend on various factors, including market competition and the number of generic entrants.

Comparison with other SGLT2 inhibitors?

Jardiance will be competing with other SGLT2 inhibitors, such as Invokana (canagliflozin) and Farxiga (dapagliflozin), which have already lost their patents. This increased competition may further push prices down and encourage more SGLT2 inhibitor development.

Can biosimilars enter before patent expiry?

Currently, it's unclear whether biosimilars of Jardiance, a biological product developed using biotechnology, can enter the market before the patent expires [4]. The regulatory pathway for biosimilars in the US is still evolving, and there may be opportunities for biosimilar developers to enter the market before the patent expires.

Sources:

[1] DrugPatentWatch.com
[2] Statnews.com
[3] Bloomberg.com
[4] BioPharmaDive.com

Note: The exact date of the patent expiration, 2027, is based on available data and may be subject to change as patent timelines can be complex.



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