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Can vascepa be combined with otc supplements Vascepa is a prescription-only pure EPA omega-3 fatty acid product. Many people who take it also use over-the-counter supplements such as fish oil, vitamin D, or curcumin. Most interactions are mild or nonexistent when taken at recommended doses. What interactions occur with common otc supplements EPA from Vascepa increases bleeding risk when combined with high-dose vitamin E, garlic supplements, or ginkgo biloba. These supplements have mild blood-thinning effects that can add to Vascepa's own anti-platelet action. Data from clinical trials show extra bleeding events mainly when users exceed 3 g/day EPA plus strong herbal blood thinners.
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