Can Lyrica (pregabalin) make you tired?
Yes. Lyrica (pregabalin) commonly causes sleepiness and fatigue in some people. This can feel like tiredness during the day, and it may also show up as drowsiness/somnolence after starting treatment or after dose increases.[1]
How soon after starting does tiredness happen?
Tiredness can appear soon after you begin taking Lyrica, and it may get worse when your dose is increased. If you notice new or worsening drowsiness after a change in dose, it’s consistent with known effects of the medication.[1]
What other effects can come with tiredness?
Along with tiredness, people may experience dizziness and impaired coordination. These effects can increase the risk of accidents, especially when driving or using machinery.[1]
Who is more likely to feel tired on Lyrica?
The label notes that sleepiness/drowsiness can be more likely depending on factors such as dose and individual sensitivity.[1] Using other medicines that also cause sedation can further increase tiredness.
What should you do if Lyrica is making you too tired?
Do not drive or do hazardous activities if you feel drowsy.[1] If tiredness is interfering with your day-to-day life, talk with your prescriber. They may adjust the dose or timing to reduce side effects.
When is tiredness a red flag?
Seek urgent help if you have severe sleepiness that is hard to stay awake from, confusion, fainting, trouble breathing, or if you have signs of an allergic reaction (such as swelling of the face/lips, hives, or difficulty breathing).[1]
Is tiredness guaranteed with Lyrica?
No. Not everyone gets tired on Lyrica, but sleepiness/fatigue is a known, common side effect.[1]
Sources
[1] https://www.accessdata.fda.gov/drugsatfda_docs/label/