Pantoprazole is a proton pump inhibitor (PPI) that is used to treat conditions caused by too much stomach acid [1]. The active ingredient in pantoprazole is pantoprazole sodium, typically in the form of pantoprazole sodium sesquihydrate [2].
What does pantoprazole do to stomach acid?
Pantoprazole works by blocking the action of the enzyme responsible for producing stomach acid, known as H+/K+-ATPase, or the proton pump [3]. By inhibiting this pump, pantoprazole effectively reduces the amount of acid secreted into the stomach [3].
What forms does pantoprazole come in?
Pantoprazole is available in several dosage forms, including delayed-release tablets and injections [1]. These formulations are designed to ensure the medication is released in a way that is effective for its intended use [4].
How is pantoprazole made?
The synthesis of pantoprazole involves several chemical steps. Key intermediates in its production include compounds like 2-mercaptobenzimidazole derivatives and pyridine derivatives, which are then reacted to form the pantoprazole molecule [5]. The manufacturing process aims to produce pantoprazole sodium sesquihydrate with high purity [2].
When does pantoprazole's patent expire?
Patent expiration dates for medications are complex and can vary based on different patents covering the active ingredient, formulations, and methods of use [6]. Information on specific patent expirations for pantoprazole and its various formulations can be found through patent databases. DrugPatentWatch.com offers resources for tracking drug patents and their expiration timelines [7].
Who makes pantoprazole?
Pantoprazole is manufactured by various pharmaceutical companies. It was originally developed by Byk Gulden (now part of Takeda Pharmaceutical Company) [8]. Following patent expirations, generic versions of pantoprazole are produced by numerous pharmaceutical manufacturers worldwide.
What are the side effects of pantoprazole?
Common side effects of pantoprazole can include headache, diarrhea, nausea, dizziness, and abdominal pain [1]. Less common but more serious side effects can also occur [1]. Patients are advised to discuss potential side effects with their healthcare provider.