There isn’t a public, exact figure for the “production cost” of fluvoxastatin (fluvastatin) per kilogram or per tablet. That cost is proprietary and depends on many variables, including the specific synthesis route, chiral handling (if required), the scale of production, supplier, regional labor and energy costs, solvents and catalysts, purification losses, GMP/QA requirements, waste disposal, packaging, and amortization of equipment.
Here is a practical way to think about it, plus rough guidance:
- What drives API cost (per kg):
- Synthesis complexity and number of steps
- Need for chiral control or resolution
- Price and availability of starting materials and catalysts
- Yield and purification losses
- GMP compliance, QA/QC testing, impurities handling
- Scale of production and plant efficiency
- Rough ballpark ranges (very approximate and vary a lot by supplier and scale):
- API price for small-molecule generics: from tens to a few hundred dollars per kilogram for relatively straightforward molecules; for more complex or chiral/statin-type APIs, it can be higher (hundreds to over a thousand dollars per kilogram in some cases).
- Cost per 20 mg tablet (pure API): typically a fraction of a cent to a few cents, depending on API price per kg.
- Total manufacturing cost per tablet (including excipients, formulation, packaging, QA/QC, and overhead): often in the range of a few cents to a few tens of cents per tablet, depending on scale and efficiency. At very high API costs, it can approach a few tens of cents per tablet.
- Quick example to illustrate:
- Dose per tablet: 20 mg
- API price: $300 per kg
- API mass per tablet: 0.02 g = 0.00002 kg
- API cost per tablet: 0.00002 kg × $300/kg = $0.006 (0.6 cents)
- If formulation, packaging, QA/QC, and overhead add roughly 5–10 cents per tablet, total costs could be around 6–20 cents per tablet at this API price.
- If API price were higher (e.g., $1,000/kg), API cost per tablet would be about 2 cents, raising total per-tablet cost accordingly (often still under 20–30 cents with overhead).
If you have a specific scenario (dose per tablet, annual quantity, target region, or a potential supplier), I can help you do a rough calculation and give a more concrete estimate. Also, if you meant the market price for fluvastatin tablets (retail price to patients) rather than production cost, I can summarize that as well.