Lipitor, also known as atorvastatin, is a medication used to treat high cholesterol levels in the blood. It belongs to a class of drugs called statins, which work by blocking an enzyme that the liver uses to make cholesterol. According to Drug Patent Watch [1], Lipitor has been on the market since 1996 and has been widely prescribed to millions of patients.

However, some people may not respond well to statins, and their cholesterol levels may remain high despite taking the medication. This is known as statin resistance. According to WebMD [2], statin resistance can occur due to various factors such as genetics, lifestyle choices, and underlying medical conditions.

When statins are not effective enough, there are other options available. Harvard Health Publishing [3] suggests that patients who are not responding to statins may benefit from other cholesterol-lowering medications such as ezetimibe, bile acid sequestrants, and PCSK9 inhibitors. Additionally, lifestyle changes such as a healthy diet, regular exercise, and quitting smoking can also help to lower cholesterol levels.

In conclusion, while Lipitor has been a widely prescribed medication for high cholesterol, it may not be effective for everyone. Statin resistance can occur due to various factors, and when this happens, there are other options available. Patients who are not responding to statins should talk to their doctor about alternative treatments and lifestyle changes that may help to lower their cholesterol levels.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.webmd.com/cholesterol-management/cholesterol-tests-statin-resistant
[3] https://www.health.harvard.edu/newsletter_article/help-for-your-cholesterol-when-the-statins-wont-do