Standard Cosentyx Dosing Schedule
Cosentyx (secukinumab) starts with loading doses, then shifts to maintenance. For plaque psoriasis, the typical adult regimen is 300 mg subcutaneous injection at weeks 0, 1, 2, 3, then every 4 weeks.[1] Psoriatic arthritis and ankylosing spondylitis follow 150-300 mg (dose based on severity) at weeks 0, 1, 2, 3, then every 4 weeks.[1][2]
How Dosing Differs by Condition
- Plaque Psoriasis: 300 mg weekly for first month, then every 4 weeks. Some switch to every 8 weeks if stable.[1]
- Psoriatic Arthritis/Ankylosing Spondylitis: 150 mg (or 300 mg if needed) weekly first month, then every 4 weeks.[2]
- Non-radiographic Axial Spondyloarthritis/Hidradenitis Suppurativa: Same as above, every 4 weeks after loading.[1]
- Pediatric Psoriasis (6+ years, 50+ kg): 300 mg loading, then every 4 weeks.[1]
Doctors adjust based on response; self-injection at home after training.
What If I Miss a Maintenance Dose?
Take it within 5 days of the missed date, then resume schedule. If over 5 days, skip and take next dose on time—don't double up.[1]
Factors That Change Frequency
Weight, response, or side effects can prompt adjustments (e.g., lower to 150 mg). Pregnancy/breastfeeding requires doctor review; no standard changes.[2] Hidradenitis suppurativa uses 300 mg every 4 weeks post-loading.[1]
[1]: Cosentyx Prescribing Information (Novartis)
[2]: Drugs.com - Cosentyx Dosage Guide