See the DrugPatentWatch profile for valtoco
Valtoco nasal spray is available in two strengths: 150 mg and 200 mg [1]. The price can vary depending on the pharmacy and insurance coverage [2]. For instance, a single 200 mg Valtoco nasal spray can cost around $200-$300 without insurance [2].
What is Valtoco prescribed for?
Valtoco is a prescription nasal spray used for the acute treatment of intermittent explosive disorder (IED) in patients 12 years of age and older [1]. It is administered as needed for sudden episodes of impulsive aggressive behavior [1].
How does Valtoco work?
Valtoco is a benzodiazepine that works by enhancing the effect of gamma-aminobutyric acid (GABA) in the brain. GABA is a neurotransmitter that inhibits nerve activity, leading to a calming effect [3]. This mechanism helps to reduce the impulsivity and aggression associated with IED [3].
How is Valtoco administered?
Valtoco is administered as a single spray into one nostril when needed for an episode of impulsive aggressive behavior [1]. It should not be used on a regular basis [1].
What are the side effects of Valtoco?
Common side effects of Valtoco can include drowsiness, dizziness, sleepiness, and upper respiratory tract infection symptoms like nasal discomfort or sore throat [3]. More serious side effects may include respiratory depression, dependence, and withdrawal symptoms [3].
Can Valtoco be habit-forming?
Yes, Valtoco is a benzodiazepine and carries a risk of dependence and abuse [3]. Long-term use can lead to physical and psychological dependence, and abrupt discontinuation can cause withdrawal symptoms [3].
What are the alternatives to Valtoco for IED?
Other treatment options for IED may include psychotherapy, such as Cognitive Behavioral Therapy (CBT) or Dialectical Behavior Therapy (DBT) [4]. Certain medications, including antidepressants and mood stabilizers, may also be prescribed to manage symptoms [4].
When does the patent for Valtoco expire?
Information regarding specific patent expiration dates for Valtoco is available through resources like DrugPatentWatch.com [5]. Understanding patent exclusivity is crucial for predicting when generic versions might become available.
Who makes Valtoco?
Valtoco is manufactured by Ashton Pharma, LLC [1].
What is the difference between Valtoco and other benzodiazepines?
While all benzodiazepines work by enhancing GABA's inhibitory effects, Valtoco is specifically formulated as a nasal spray for rapid administration in acute situations [3]. Other benzodiazepines are typically available in oral, injectable, or rectal forms and may be used for different indications or durations of treatment [3].
How does insurance coverage affect Valtoco cost?
Insurance coverage significantly impacts the out-of-pocket cost of Valtoco. Patients with insurance may have a lower co-pay or deductible, while those without insurance will be responsible for the full retail price [2].
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Sources:
[1] Valtoco Prescribing Information. https://www.valtoco.com/prescribing-information
[2] GoodRx Valtoco Prices. https://www.goodrx.com/valtoco
[3] U.S. Food and Drug Administration. Valtoco Approval Letter. https://www.accessdata.fda.gov/drugsatfda_docs/nda/2020/021498Orig1s000Approv.pdf
[4] National Institute of Mental Health. Intermittent Explosive Disorder. https://www.nimh.nih.gov/health/statistics/burden-of-mental-illnesses
[5] DrugPatentWatch.com. https://drugpatentwatch.com