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See the DrugPatentWatch profile for Lisinopril
Lisinopril is an ACE inhibitor (angiotensin-converting enzyme inhibitor). [1]
Lisinopril lowers blood pressure by blocking ACE, the enzyme that helps produce angiotensin II. Angiotensin II normally causes blood vessels to tighten (narrow) and increases aldosterone-driven salt and water retention. By reducing angiotensin II, lisinopril helps blood vessels relax and reduces fluid retention, which lowers overall blood pressure. [1]
By decreasing angiotensin II formation, ACE inhibitors reduce vasoconstriction (narrowing of arteries) and tend to lower the body’s tendency to retain salt and water through aldosterone effects. The combined result is lower vascular resistance and lower blood pressure. [1] Sources: [1] https://www.drugs.com/lisinopril.html
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