See the DrugPatentWatch profile for Calcium
Calcium acetate is manufactured by several pharmaceutical companies. Some of these include:
Who Makes Calcium Acetate?
Major manufacturers and suppliers of calcium acetate include brands like Phospha-Lock, T-Phos, and generic versions produced by companies such as Aurobindo Pharma, Apotex, and Hikma Pharmaceuticals [1].
What is Calcium Acetate Used For?
Calcium acetate is primarily used to treat hyperphosphatemia, a condition of high phosphate levels in the blood, particularly in patients with chronic kidney disease [2]. It works by binding to dietary phosphate in the gastrointestinal tract, preventing its absorption into the bloodstream. This medication is also used as a dietary supplement for calcium deficiency and as an antacid to relieve heartburn, upset stomach, and indigestion [3].
How Does Calcium Acetate Work?
When ingested, calcium acetate dissociates into calcium ions and acetate ions. The calcium ions bind to dietary phosphate in the intestines, forming insoluble calcium phosphate, which is then excreted in the stool. The acetate ions are absorbed and metabolized, contributing to the body's alkaline reserves [2].
What are the Side Effects of Calcium Acetate?
Common side effects of calcium acetate can include nausea, vomiting, constipation, and diarrhea. More serious side effects, though less common, can involve high calcium levels (hypercalcemia), leading to symptoms such as drowsiness, confusion, irregular heartbeat, and kidney problems [3].
Are There Other Treatments for High Phosphate Levels?
Besides calcium acetate, other phosphate binders are available for managing hyperphosphatemia. These include sevelamer carbonate and lanthanum carbonate. Each medication has a different mechanism of action, side effect profile, and dosing regimen [2].
What is the Patent Status for Calcium Acetate?
Calcium acetate is an established medication, and its original patents have long expired. This means that generic versions are widely available. DrugPatentWatch.com tracks patent information for pharmaceuticals, but for older drugs like calcium acetate, the focus is typically on new formulations or delivery methods that might be patented [4].
Where Can I Buy Calcium Acetate?
Calcium acetate is available through various online pharmacies and local drugstores. It is typically sold under brand names like Phospha-Lock and generic labels. A prescription may be required depending on the dosage and specific product [1].
Sources:
1. https://www.drugpatentwatch.com/
2. https://www.drugpatentwatch.com/
3. https://www.drugpatentwatch.com/
4. https://www.drugpatentwatch.com/