Standard Adult Dosage for Plaque Psoriasis and Psoriatic Arthritis
Cosentyx (secukinumab) starts with a 300 mg subcutaneous dose at weeks 0, 1, 2, 3, and 4, followed by 300 mg every 4 weeks. Some patients drop to 150 mg every 4 weeks if they respond well and have milder disease.[1]
Dosage for Ankylosing Spondylitis and Non-Radiographic Axial Spondyloarthritis
Loading dose is 150 mg subcutaneously at weeks 0, 1, 2, 3, and 4, then 150 mg every 4 weeks. For patients under 150 mg who don't respond, doctors may increase to 300 mg.[1]
Pediatric Dosages for Psoriatic Arthritis and Enthesitis-Related Arthritis
Children 2 years and older weighing at least 15 kg get weight-based dosing: 75 mg (15-50 kg) or 150 mg (>50 kg) at weeks 0, 1, 2, 3, 4, then every 4 weeks. Use 75 mg or 150 mg prefilled syringes or autoinjectors.[1]
Dosage for Moderate to Severe Hidradenitis Suppurativa
Initial 300 mg subcutaneously at weeks 0, 1, 2, 3, 4, then 300 mg every 4 weeks.[1]
How It's Administered and Adjusted
All doses are subcutaneous, self-injected into the thigh, abdomen, or upper arm using prefilled syringes, autoinjectors, or a 1 mL pen. No loading dose for some indications like Crohn's disease (300 mg at weeks 0, 1, 2, 3, 4, then every 4 weeks). Doctors adjust based on response, weight, or side effects; missed doses should be taken as soon as possible within 7 days.[1]
Common Questions on Dosage Changes or Missed Doses
If a dose is missed by more than 7 days, skip it and resume the schedule. Weight affects pediatric dosing but not adult fixed doses. No IV option exists; all are subcutaneous.[1]
[1]: https://www.cosentyx.com/ (official dosing from Novartis product information)