Higher doses of Lipitor, a medication commonly prescribed to lower cholesterol levels, can increase the risk of certain side effects. According to the Lipitor Prescribing Information provided by the U.S. Food and Drug Administration (FDA) [1], some of the common side effects associated with Lipitor include diarrhea, upset stomach, muscle and joint pain, and changes in some laboratory tests.

More serious side effects that may occur with higher doses of Lipitor include myopathy (muscle damage) and rhabdomyolysis (a serious condition that can cause kidney damage) [1]. The risk of these side effects may increase with higher doses of Lipitor or when Lipitor is used in combination with certain other medications [1].

It is important to note that the benefits of Lipitor in reducing the risk of heart attack and stroke generally outweigh the risks of these side effects [1]. However, patients should discuss any concerns about the potential side effects of Lipitor with their healthcare provider.

In addition, it is important to follow the dosage instructions provided by a healthcare provider carefully, as taking higher doses of Lipitor than prescribed can increase the risk of side effects [1].

Sources:

1. Lipitor Prescribing Information. U.S. Food and Drug Administration. <https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/020272s052lbl.pdf>. Accessed 2023-03-15.

Additional sources:

* Lipitor. DrugPatentWatch.com. <https://www.drugpatentwatch.com/drugs/lipitor>. Accessed 2023-03-15.
* Lipitor. Mayo Clinic. <https://www.mayoclinic.org/drugs-supplements/lipitor-oral-route/side-effects/drg-20064530>. Accessed 2023-03-15.
* Lipitor. MedlinePlus. <https://medlineplus.gov/druginfo/meds/a601204.html>. Accessed 2023-03-15.