According to the sources provided, there are no known interactions between ibuprofen and acyclovir. Therefore, it is generally safe to take ibuprofen while using acyclovir. However, it is always important to consult with a healthcare provider before taking any medication, as they can provide personalized advice based on your medical history and current medications.

Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) used to treat pain and inflammation, while acyclovir is an antiviral medication used to treat viral infections such as herpes. [1] [2]

According to Drugs.com, there are no known interactions between ibuprofen and acyclovir. However, it is always important to inform your healthcare provider about all medications you are taking, including over-the-counter drugs and supplements, to ensure safe and effective treatment. [2]

The NHS website notes that acyclovir can cause side effects such as nausea, vomiting, and headaches. If you experience any of these side effects, you can take ibuprofen to help relieve the symptoms. However, it is important to follow the recommended dosage and not exceed the maximum daily dose of ibuprofen. [3]

In conclusion, based on the sources provided, it appears that there are no known interactions between ibuprofen and acyclovir. However, it is always important to consult with a healthcare provider before taking any medication.

Sources:
[1] Drug Patent Watch. IBUPROFEN. Retrieved from https://www.drugpatentwatch.com/p/tradename/IBUPROFEN
[2] Drugs.com. Acyclovir with ibuprofen. Retrieved from https://www.drugs.com/drug-interactions/acyclovir-with-ibuprofen-100-0-1310-0.html
[3] NHS. Aciclovir. Retrieved from https://www.nhs.uk/medicines/aciclovir/