Erythromycin produced by saccharopolyspora erythraea source?

What is the source organism that produces erythromycin?

Erythromycin is produced by the bacterium Saccharopolyspora erythraea (a soil-dwelling actinobacterium). This organism is used industrially to biosynthesize erythromycin as an antibiotic product. [1]

How does Saccharopolyspora erythraea make erythromycin?

In Saccharopolyspora erythraea, erythromycin is produced through the organism’s secondary-metabolite biosynthetic pathway, generating the macrolide antibiotic as a natural product. The key point for sourcing is that the producing microorganism is Saccharopolyspora erythraea itself. [1]

Is erythromycin always made from Saccharopolyspora erythraea?

Erythromycin has historically been produced by fermentation using Saccharopolyspora erythraea. Alternative manufacturing routes may exist (such as semi-synthetic modification of fermentation-derived intermediates), but the classic biological producing source is Saccharopolyspora erythraea. [1]

Practical use: what does this mean for “erythromycin from Saccharopolyspora erythraea”?

When a product or process description says it uses Saccharopolyspora erythraea as the source, it means the antibiotic is biosynthesized during microbial fermentation with this bacterium and then recovered and purified to make erythromycin. [1]

Source

1. https://en.wikipedia.org/wiki/Saccharopolyspora_erythraea