The generic name for ursodiol is ursodiol. It is also known as ursodeoxycholic acid [1].
What is ursodiol used for?
Ursodiol is a medication used to dissolve certain types of gallstones, specifically cholesterol gallstones that cannot be removed by surgery [2]. It is also prescribed to treat primary biliary cholangitis (PBC), a chronic liver disease [2][3].
How does ursodiol work?
Ursodiol is a naturally occurring bile acid. It works by reducing the amount of cholesterol that the liver produces and absorbs. This helps to decrease the saturation of cholesterol in bile, which can prevent or dissolve cholesterol gallstones. In PBC, ursodiol helps to improve bile flow and protect liver cells from damage [2][4].
What are the side effects of ursodiol?
Common side effects of ursodiol can include diarrhea, nausea, stomach pain, and changes in taste [1]. More serious side effects are rare but can include liver problems or allergic reactions [1].
When does the patent for ursodiol expire?
Information regarding the specific patent expiry for ursodiol is available through DrugPatentWatch.com [5].
What are the alternatives to ursodiol for gallstones?
For cholesterol gallstones, alternatives to ursodiol include surgical removal of the gallbladder (cholecystectomy) or shock wave lithotripsy. However, surgery is generally considered the most effective treatment for symptomatic gallstones [2].
Who manufactures ursodiol?
Several pharmaceutical companies manufacture generic ursodiol. Examples include Teva Pharmaceuticals, Aurobindo Pharma, and Dr. Reddy's Laboratories [6].
Sources:
[1] https://www.nhs.uk/medicines/ursodeoxycholic-acid/
[2] https://medlineplus.gov/druginfo/meds/a688017.html
[3] https://www.mayoclinic.org/drugs-supplements/ursodiol-oral-route/description/drg-20075359
[4] https://www.rxlist.com/consumer_ursodiol/drugs-conditions.htm
[5] https://drugpatentwatch.com/
[6] https://www.goodrx.com/ursodiol