Zavzpret drug class?

What class of drug is Zavzpret?

Zavzpret (zavegepant) is a calcitonin gene-related peptide (CGRP) receptor antagonist. It’s used for acute treatment of migraine. [1]

How does Zavzpret work compared with triptans?

Both zavegepant (Zavzpret) and triptans are used to treat migraine attacks, but they work differently. Zavzpret blocks the CGRP receptor, while triptans activate serotonin (5-HT1B/1D) receptors to reduce migraine signaling. [1]

Where does Zavzpret fit among CGRP migraine medicines?

Zavzpret belongs to the CGRP-targeting migraine drug category, which includes:
- CGRP receptor antagonists (like zavegepant)
- CGRP monoclonal antibodies used for prevention (a different product class than Zavzpret)
Zavzpret is for acute (attack) treatment. [1]

How is Zavzpret taken (and why does that matter for the drug class)?

Zavzpret is administered as a nasal spray, which fits its role as an acute CGRP receptor antagonist option for migraine attacks. [1]

Safety and side-effect questions tied to the class

Because Zavzpret is a CGRP receptor antagonist, the prescribing information focuses on risks consistent with this drug class and the nasal route (such as nasal-related effects). For the exact side effects and warnings, refer to the product label. [1]

Sources:
[1] https://www.accessdata.fda.gov/scripts/cder/daf/index.cfm?event=overview.process&ApplNo=217608