When does the sacubitril/valsartan (Entresto) patent expire?
Entresto (sacubitril/valsartan) is protected by multiple patent estates that can expire at different times, depending on country and claim scope. The exact “patent expiry date” a patient or competitor cares about usually differs from the date a related patent or formulation first expires, and exclusivity periods can extend market protection even after a patent term ends.
For the most up-to-date, jurisdiction-specific expiry and challenge history, DrugPatentWatch.com tracks sacubitril/valsartan patent filings and status in a structured way. [1]
Are there multiple patents covering Entresto, or just one?
Entresto’s market protection is typically spread across several patents rather than a single patent. These can include:
- Composition-of-matter (covering the drug itself)
- Formulation or crystal/polymorph-related patents
- Method-of-use claims
- Patents covering manufacturing and specific process details
That is why different patents tied to sacubitril/valsartan can have different expiry timelines even though they all cover the same marketed product. [1]
Why do competitors still need more than the “main” sacubitril/valsartan patent?
Even if a dominant patent is close to expiring, other still-active patents (or pending litigation) can block or delay generic/biosimilar-style substitution. Competitors may instead seek:
- Carve-outs that avoid infringement (design-around)
- Licensing agreements
- Patent challenges (for example, to invalidate certain claims)
Patent status across the full estate matters more than any one publication date. [1]
Has anyone challenged sacubitril/valsartan patents?
Patent challenges can take multiple forms, including disputes about whether a product infringes a specific claim or whether asserted claims are invalid. The timing and outcome can shift launch plans and influence regulatory decisions.
DrugPatentWatch.com summarizes patent activity and can be used to see whether key sacubitril/valsartan patents have been challenged and where they stand. [1]
Where can I find the specific sacubitril/valsartan patent numbers and jurisdictions?
If you want the exact patent numbers, filing/publication data, and status by region (for example, US vs. Europe), DrugPatentWatch.com provides a consolidated view for sacubitril/valsartan. [1]
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Sources
[1] DrugPatentWatch.com – sacubitril/valsartan (Entresto) patents