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See the DrugPatentWatch profile for Nicotine
Nicotine polacrilex is the nicotine gum form of nicotine replacement therapy. The nicotine is bound to a polacrilex resin to slow its release in the mouth, helping you quit smoking by delivering nicotine as you chew. Key points: - Brand/name: Nicotine gum (e.g., Nicorette). The active ingredient is nicotine bound to polacrilex. - Who it’s for: Adults who want to quit smoking or reduce smoking. Not for non-smokers or anyone under 18 without a clinician’s guidance. - How to use (typical method): - Chew one piece slowly until you taste a peppery/tingling sensation. - Park the gum between your cheek and gum to absorb nicotine. - When the taste/tingling fades, chew again a few times, then park again. Don’t swallow the gum; repeat as directed. - Dosing (general guidelines): - Strengths: 2 mg and 4 mg. - Use 4 mg if you smoke more than about 20 cigarettes per day or if your first cigarette is within 30 minutes of waking; otherwise 2 mg. - Try to use at least several pieces per day initially, then gradually reduce over about 6–12 weeks. - Maximum typically around 24 pieces per day. - Common side effects: Mouth soreness or irritation, jaw ache, hiccups, indigestion, changes in taste, mouth ulcers. - Precautions: - Not for use in pregnant/breastfeeding individuals without medical advice. - Not suitable for people with severe mouth ulcers or TMJ problems that chewing aggravates. - If you have heart disease or other medical conditions, check with a clinician. - Interactions: No major drug interactions, but nicotine can affect heart rate and blood pressure; tell your clinician about all meds you're taking. - When to seek help: Chest pain, severe allergic reaction, trouble breathing, or if you can’t quit after a course of therapy. If you’d like, tell me how many cigarettes you smoke per day (and any health considerations), and I can tailor a dosing/start plan and a quit timeline.
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