Ripretinib synthesis urea?

I can help, but the phrase “Ripretinib synthesis urea” is ambiguous. Do you mean:

1) the role of a urea group in ripretinib’s structure (how that part is made),
2) a urea-based intermediate used in ripretinib synthesis, or
3) a specific patented “urea synthesis” step for ripretinib?

What I can do next (pick one)
- If you want the chemistry: tell me whether you need the urea formation method (e.g., coupling a carboxylate derivative to an amine/urea synthon, or transforming an isocyanate), and what level of detail (high-level vs. step-by-step).
- If you want patents: share the patent number or link you’re looking at, or confirm you want a patent-style description of the urea-forming step.
- If you want structure context: confirm whether you mean the urea/urethane-like linkage present in ripretinib (just describe it as “the urea linker”).

Reply with which of the three you meant (and any link/patent you’re referencing), and I’ll write a focused answer around that.