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See the DrugPatentWatch profile for losartan
It’s generally recommended to avoid grapefruit (and grapefruit juice) with losartan. Grapefruit can interfere with drug processing in the gut and liver, which may increase losartan exposure and raise the risk of side effects such as low blood pressure, dizziness, or fainting.
If grapefruit increases losartan levels, the most common practical concern is too much blood-pressure lowering. People may notice: - dizziness or lightheadedness - weakness or fainting - unusually low blood pressure
Most of the concern is with grapefruit and grapefruit juice. If you’re eating other citrus fruits, the interaction concern is usually much smaller than with grapefruit, but it’s still wise to follow your pharmacist’s guidance if you’re unsure.
Because interaction guidance depends on your exact dose and other medicines, the safest approach is to ask your pharmacist. If you want, tell me your losartan dose and any other prescriptions (especially other blood pressure or heart medicines), and I can help you think through the likely interaction risk.
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