Lipitor is a medication used to lower cholesterol levels in the body. According to the sources provided, it is not safe to take Lipitor with grapefruit juice. Grapefruit juice can interact with Lipitor, increasing the risk of side effects. Lipitor is metabolized in the liver by an enzyme called CYP3A4. Grapefruit juice contains compounds that can inhibit this enzyme, leading to increased levels of Lipitor in the bloodstream [3]. This can increase the risk of side effects, such as muscle pain, liver damage, and kidney problems [2].

Verywell Health recommends that patients avoid consuming grapefruit or grapefruit juice while taking Lipitor [2]. Harvard Health Publishing also advises against consuming grapefruit juice or grapefruit products while taking Lipitor [3]. Drug Patent Watch also notes that grapefruit juice can interact with Lipitor, increasing the risk of side effects [1].

In conclusion, it is not safe to take Lipitor with grapefruit juice. Patients should avoid consuming grapefruit or grapefruit juice while taking Lipitor to reduce the risk of side effects. It is important to talk to a healthcare provider about any concerns or questions regarding the use of Lipitor.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.verywellhealth.com/can-i-take-lipitor-or-zocor-with-grapefruit-juice-1124045
[3] https://www.health.harvard.edu/heart-health/grapefruit-juice-and-statins