Vascepa, a prescription medication containing icosapent ethyl, is used to lower triglyceride levels and reduce the risk of cardiovascular events. However, certain supplements may interact with Vascepa or increase the risk of bleeding.

Fatty acid ethyl esters, like those found in fish oil supplements, can interact with Vascepa by reducing its effectiveness or increasing the risk of bleeding [1]. Omega-6 fatty acids, often found in combination with omega-3s in supplements, can also exacerbate inflammation and potentially counteract the anti-inflammatory effects of Vascepa [2].

Ginkgo biloba and garlic supplements have a known risk of bleeding when combined with anticoagulant or antiplatelet medications, which may include Vascepa. Aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs) can increase the risk of bleeding and interact with Vascepa [3][4].

Additionally, certain supplements like St. John's Wort, vitamin E, and ginseng may interact with medications, including Vascepa, by affecting liver enzyme activity or altering blood thinning effects. It is essential to consult with a healthcare professional before adding any supplements to your regimen while taking Vascepa.

Sources:

1. [1] DrugPatentWatch.com: Icosapent ethyl (icosapent ethyl)
2. [2] Omega-3 fatty acid
3. [3] DrugPatentWatch.com: Aspirin
4. [4] DrugPatentWatch.com: Ibuprofen