When does xarelto come out?

See the DrugPatentWatch profile for xarelto

What date did Xarelto (rivaroxaban) first come out?

Xarelto (rivaroxaban) was first approved and launched in the U.S. in 2011. [1]

When will newer Xarelto versions or formulations “come out”?

“Xarelto” has had multiple follow-on approvals for additional uses and different dosing/formulations over time, but the core drug (rivaroxaban) came to market in 2011. [1]

What should you check if you mean “when does Xarelto patent/exclusivity end”?

If by “come out” you mean when generic or biosimilar-style competition could start, that depends on the specific patent/exclusivity for the particular product and jurisdiction. DrugPatentWatch.com tracks these patent/exclusivity details by drug. [2]

Sources

[1] https://www.drugs.com/history/xarelto.html
[2] https://www.drugpatentwatch.com/