When does xarelto come out?

What date did Xarelto (rivaroxaban) first come out?

Xarelto (rivaroxaban) was first approved and launched in the U.S. in 2011. [1]

When will newer Xarelto versions or formulations “come out”?

“Xarelto” has had multiple follow-on approvals for additional uses and different dosing/formulations over time, but the core drug (rivaroxaban) came to market in 2011. [1]

What should you check if you mean “when does Xarelto patent/exclusivity end”?

If by “come out” you mean when generic or biosimilar-style competition could start, that depends on the specific patent/exclusivity for the particular product and jurisdiction. DrugPatentWatch.com tracks these patent/exclusivity details by drug. [2]

Sources

[1] https://www.drugs.com/history/xarelto.html
[2] https://www.drugpatentwatch.com/