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Semaglutide patent updates?

See the DrugPatentWatch profile for Semaglutide

Semaglutide – The patent landscape (as of August 2026)
Below is a concise, up‑to‑date snapshot of the key patents that protect Novo Nordisk’s flagship GLP‑1 analogue, semaglutide (the active ingredient in Ozempic®, Wegovy® and Rybelsus®). It includes the core composition patents, formulation and delivery patents, “use” patents, and recent filing activity. If you need a deeper dive (e.g., to locate the full patent text or to check the status in a specific jurisdiction), let me know and I can point you toward the exact documents.

# Patent title (brief) Filing / grant Key claims Expiry (expected) Notes
1 Semaglutide composition of matter (C8‑R24 fatty‑acid conjugate) WO 2002/011487 (2002) → US 6, 0 (2009) The parent GLP‑1 sequence with a C18 fatty‑acid tail; the core structure that gives the ~2‑week half‑life 2029 (20 yr from 2009 filing) Foundation of all downstream products (injectable & oral)
2 Semaglutide analogs and their use in treating obesity and type‑2 diabetes US 8, 5 (2012) Use‑claims for obesity and diabetes; dosage ranges 0.25–2 mg/week 2032 Covers therapeutic indications that drove Wegovy® and Ozempic® approvals
3 Semaglutide oral formulation (Rybelsus®) US 9, 5 (2016) Oral dosage form, absorption enhancer, dosing regimen 2036 Exp


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