Official Shelf Life for Neffy
Neffy (epinephrine nasal spray) has a shelf life of 18 months from the date of manufacture when unopened and stored at controlled room temperature (20-25°C or 68-77°F), protected from light.[1]
How to Check Expiration on Your Neffy
Expiration dates are printed on the carton and each nasal spray device. Once opened, use immediately—do not store for later use. Discard any expired product.[1][2]
Storage Requirements to Maximize Shelf Life
Keep unopened Neffy in its original carton, away from extreme heat, cold, or direct sunlight. Avoid freezing or temperatures above 30°C (86°F). No refrigeration needed.[1]
What Happens After Expiration?
Expired Neffy may deliver reduced epinephrine dose, risking ineffective treatment for anaphylaxis. Replace before expiration; carry two doses as recommended.[2][3]
How Neffy Shelf Life Compares to EpiPen
Neffy lasts 18 months unopened, matching EpiPen's typical shelf life. Both auto-injectors and Neffy require immediate use after opening and annual replacement checks.[3]
[1] Neffy Prescribing Information, https://neffy.com/wp-content/uploads/2024/08/Neffy-PI-Clean-Final-8.16.24.pdf
[2] FDA Approval Label for Neffy, https://www.accessdata.fda.gov/drugsatfda_docs/label/2024/209991s000lbl.pdf
[3] EpiPen Prescribing Information, https://www.epipen.com/-/media/files/epipen/pi/epipen-pi.pdf