What is Kepivance?
Kepivance is a brand name for a medicine called palifermin. Palifermin is a form of a manufactured protein (a keratinocyte growth factor, or KG F) that helps protect and repair the lining of the mouth and throat. It is used to reduce oral mucositis—painful mouth sores—often caused by cancer treatments like chemotherapy and/or radiation. [1]
What condition is it used for?
Kepivance is used for severe oral mucositis in people receiving cancer therapy, especially when treatment is expected to cause significant damage to the mouth lining. By helping the mucosa recover, it can reduce the severity and duration of these mouth sores. [1]
How does it work?
Kepivance (palifermin) is designed to stimulate healing in the epithelial cells of the mouth and throat. That growth-factor activity supports regeneration of the damaged mucosal lining after chemotherapy and/or radiation. [1]
How is it given?
Kepivance is administered as an IV (intravenous) infusion by a healthcare professional, and the dosing schedule is planned around the timing of chemotherapy and/or radiation. [1]
Where can I verify details like dosing and safety?
Because specific use depends on the exact cancer treatment plan and patient factors, the most reliable details on dosing, timing, and side effects come from the prescribing information and your oncology team. [1]
Sources
[1] https://www.accessdata.fda.gov/scripts/cder/daf/index.cfm?event=overview.process&ApplNo=762196