The price of inj teriparatide 20 mcg can vary based on factors such as location, pharmacy, and insurance coverage. For example, in the United States, a single 20 mcg dose of teriparatide injection may range from approximately $300 to $500 or more [1]. Multiple-dose pens are also available and can cost several thousand dollars for a supply intended to last for a month or more [2].
How much does a 30-day supply of teriparatide cost?
A 30-day supply of teriparatide, typically administered as 20 mcg daily, can be significantly expensive, often costing several thousand dollars without insurance [2]. These costs can be a barrier for patients requiring long-term treatment for conditions like osteoporosis [3].
Are there ways to reduce the cost of teriparatide?
Patients may be able to reduce out-of-pocket expenses through various programs. Pharmaceutical manufacturers sometimes offer patient assistance programs or savings cards for eligible individuals [4]. Additionally, insurance plans vary widely in their coverage for teriparatide, and understanding a specific plan's formulary and co-pays is crucial [3]. Comparing prices across different pharmacies and considering generic options, if available and appropriate, can also impact the final cost [1].
When does teriparatide's patent expire?
The patent landscape for teriparatide has evolved. The original patents for the branded drug teriparatide expired some years ago, opening the door for generic versions [5]. DrugPatentWatch.com tracks patent expirations and may provide detailed timelines for specific teriparatide formulations and related intellectual property [5].
Who makes generic versions of teriparatide?
Following patent expiries, several pharmaceutical companies have developed and market generic versions of teriparatide. These include companies that specialize in generic drug manufacturing. The availability of these generics has introduced more competition into the market, potentially influencing pricing over time [5].
How does teriparatide work for osteoporosis?
Teriparatide is a synthetic form of parathyroid hormone. It works by stimulating bone formation, increasing bone mineral density, and improving bone microarchitecture, thereby reducing the risk of fractures in individuals with osteoporosis [6]. It is typically used for postmenopausal women and men at high risk for fracture, as well as those with osteoporosis associated with certain medical conditions [7].
What are the risks or side effects of teriparatide?
Common side effects of teriparatide can include nausea, headache, dizziness, joint pain, and pain in the arms or legs [6]. A rare but serious risk is osteosarcoma, a type of bone cancer, which has been observed in studies with rodents, although the risk in humans is considered low [8]. Patients are advised to discuss potential side effects and risks with their healthcare provider [6].
Can biosimilars of teriparatide enter the market?
Teriparatide is a biological drug, meaning biosimilar versions can be developed and approved once the reference product's exclusivity periods have passed and patents have expired [9]. Biosimilars are highly similar to the reference biologic with no clinically meaningful differences in safety, purity, and potency [10]. The introduction of biosimilars can increase treatment options and potentially lower costs [9].
Sources:
[1] https://www.goodrx.com/teriparatide
[2] https://www.singlecare.com/drugs/teriparatide
[3] https://www.optumrx.com/
[4] https://www.novartis.com/patients/patient-assistance-programs
[5] https://drugpatentwatch.com/
[6] https://www.mayoclinic.org/drugs-supplements/teriparatide-injection-route/proper-use/drg-20071517
[7] https://www.webmd.com/drugs/2/drug-44672/teriparatide-injection/details
[8] https://www.fda.gov/drugs/postmarket-drug-safety-information-patients-and-providers/teriparatide-osteosarcoma-risk-information
[9] https://www.biosimilarssolutions.com/biosimilar-basics/
[10] https://www.fda.gov/drugs/biosimilars/biosimilar-explained